Chikungunya fever typically begins abruptly 3-7 days after the bite of an infected female Aedes mosquito with the following key signs and symptoms:
- High-grade fever: Temperature often >39°C or 102°F
- Severe joint pain and swelling: usually bilateral and symmetric, affecting wrists, fingers, ankles, and knees; the pain can be debilitating and may last weeks to years.
- Headache:
- Muscle Pain (myalgia)
- Rash: Usually maculopapular on the torso and limbs.
- Nausea and Vomiting
- Fatigue and malaise
- Conjunctivitis
- Lymphadenopathy (swelling of lymph nodes)
Rare but serious complications can include uveitis, retinitis, myocarditis, hepatitis, nephritis, and neurological complications like meningoencephalitis, Guillain-Barré syndrome, and cranial nerve palsies.
Severe disease and complications are more common in neonates (infected around birth), elderly people, and those with underlying medical conditions.
Most patients recover in days to weeks, but joint pain can persist for months or years, causing chronic arthritis-like symptoms. Deaths are rare.
Distinguish Chikungunya symptoms from Dengue and Zika virus
Chikungunya, dengue, and Zika virus have overlapping symptoms but also distinct features to help differentiate them clinically
| Sr. no. | Feature | Chikungunya | Dengue | Zika |
| 1 | Fever | Sudden high fever, often >102°F | High fever, sudden onset | Usually mild or low-grade fever |
| 2 | Joint pain | Severe, debilitating, symmetrical polyarthralgia common | Mild or absent | Mild to moderate arthralgia |
| 3 | Rash | Maculopapular rash on face, hands, feet, and limbs, less itchy | Rash on limbs and face, often itchy | Maculopapular rash, often itchy, and conjunctivitis are common |
| 4 | Headache | Present | Severe, often with retro-orbit pain | Mild to moderate |
| 5 | Muscle pain (myalgia) | Common | Common | Common |
| 6 | Conjunctivitis | Occasionally | Rare | Common |
| 7 | Bleeding Tendency | Rare | Common ,risk of hemorrhagic manifestation | Rare |
| 8 | Severe Complication | Chronic arthritis ,rare complication neurological | Dengue hemorrhagic fever and shock syndrome possible | Neurological complications; congenital infections in fetus (microcephaly) |
| 9 | Duration of symptoms | Fever lasts 2-7 days; joint pain can persist for months | Fever usually 2-7 days; recovery is longer in severe cases | Usually lasts less than a week |
Treatment on Chikungunya Fever
Chikungunya fever has no specific antiviral treatment or vaccine, focusing instead on symptom relief. Supportive care emphasizes rest, hydration, and pain management to ease fever, joint pain, and rash. Paracetamol is the preferred medication for fever as well as pain reduction.
Acute Phase Management
Patients receive fluids, electrolytes, and analgesics during the initial 3-7 days of high fever and severe arthralgia. Avoid aspirin and NSAIDs like ibuprofen to prevent bleeding risks from potential co-infection with dengue fever especially. Hospitalization is rare but needed for dehydration or severe symptoms.
Chronic Symptom Management
Persistent joint pain lasting weeks to years affects up to 50% of cases and may require NSAIDs once dengue is ruled out. Physiotherapy and natural remedies like homeopathy offer adjunct relief in some settings.

